Exercise can lead to a decrease in plasma glutamine levels. Studies have shown that power athletes can have particularly low plasma glutamine. It also affects endurance athletes after running a marathon, glutamine levels are low for 6-9 hours. Low plasma glutamine is an indicator of overtraining. Glutamine has been linked with the following: Improved gut barrier function and reduced risk of endotoxaemia Nutritional support for immune system and prevention of infection Stimulation of muscle glycogen re-synthesis Stimulation of muscle protein synthesis and muscle tissue growth Reduction in muscle soreness and improved muscle tissue repairGlutamine deficiency has been observed after surgery, burns and other stresses as well as exercise. For this reason it is called a conditionally essential amino acid.
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